(Sophronius, a native of the Cappadocian Cæsarea, was an early friend and fellow-student of Gregory and Basil. He entered the Civil Service, and soon rose to high office. In a.d.365 he was appointed Prefect of Constantinople, as a reward for timely intimation which he gave to the Emperor Valens of the usurpation attempted by Procopius. He is chiefly known to us by the letters of Gregory and Basil, invoking his good offices for various persons. Ep.21 was written in a.d.369 to commend to him Nicobulus, Gregory's nephew by marriage, the husband of Alypiana, daughter of his sister Gorgonia. This Nicobulus was a man of great wealth and ability, but much disinclined for public life. Gregory constantly writes to one and another high official to get him excused from appointments which had been thrust upon him.)