Other scriptures warning against ignoring God?
What other scriptures warn against ignoring God's truth and wisdom?

Romans 1:28—Our Launch Point

“Furthermore, just as they did not think it worthwhile to retain the knowledge of God, God gave them over to a depraved mind, so that they do what ought not to be done.”

Paul’s warning is clear: despising God’s revealed truth eventually results in a mind unable to choose what is right. Scripture consistently repeats this caution.


Wisdom’s Call Rejected – Proverbs 1:24-31

“Because you refused to listen when I called … they will eat the fruit of their own way and be filled with their own devices.”

• Ignoring God’s wisdom leaves people to the bitter harvest of their own choices.

• The same “gave them over” idea in Romans 1 appears here: God lets stubborn hearts experience the consequences they insist on.


Despising Instruction – Proverbs 13:13

“He who despises instruction will pay the penalty, but the one who respects a command is rewarded.”


Religious Ritual without Submission – Proverbs 28:9

“If anyone turns a deaf ear to the law, even his prayer is detestable.”

Turning from truth corrupts even outward acts of worship.


My People Destroyed for Lack of Knowledge – Hosea 4:6

“My people are destroyed for lack of knowledge. Because you have rejected knowledge, I also will reject you…”


Woe to Those Who Rename Evil – Isaiah 5:20-24

“Woe to those who call evil good and good evil … Therefore, as tongues of fire consume straw … so their root will be as rot.”

• Redefining morality invites judgment.

• The “depraved mind” of Romans 1 shows up here as moral reversal.


Stiff-Necked Hearts – Zechariah 7:11-13

“But they refused to pay attention … therefore great wrath came from the LORD … ‘Just as they would not listen when I called, so I would not listen when they called,’ says the LORD of Hosts.”


Calamity for Ignoring God’s Word – Jeremiah 6:19

“Listen, O earth! I am bringing disaster on this people, the fruit of their own schemes, because they have not listened to My words and have rejected My instruction.”


The Lie Embraced – 2 Thessalonians 2:10-12

“They perish because they refused to love the truth and so be saved. For this reason God will send them a powerful delusion so that they will believe the lie…”

The New Testament repeats the pattern of Romans 1: persistent refusal becomes judicial delusion.


Drifting and Hardening – Hebrews

Hebrews 2:1-3 – “…how shall we escape if we neglect so great a salvation?”

Hebrews 3:12-13 – “Beware, brethren, lest there be in any of you an evil, unbelieving heart that turns away from the living God.”

Hebrews 12:25 – “See to it that you do not refuse Him who is speaking.”


Itching Ears – 2 Timothy 4:3-4

“For the time will come when men will not tolerate sound doctrine … they will turn their ears away from the truth and turn aside to myths.”


Self-Deception – James 1:22

“Be doers of the word, and not hearers only, deceiving yourselves.”


Scoffers in the Last Days – 2 Peter 3:3-7

“Mockers will come with their mocking … they deliberately overlook this fact … the present heavens and earth are reserved for fire.”


A Thread Running Through Scripture

• God graciously offers truth and wisdom.

• Rejection is never neutral; it reshapes the mind and invites judgment.

• From Proverbs to Revelation, the Spirit warns that ignoring or redefining God’s word leads to delusion, destruction, and lost fellowship.

Romans 1:28 is part of this grand, sobering chorus: when people trade God’s wisdom for their own, God eventually lets them live with the full weight of that exchange.

How can we guard against a 'depraved mind' in our daily lives?
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