What is the meaning of Isaiah 45:22?

Turn to Me

God’s first word is an urgent invitation. He does not say, “Try harder” or “Work your way up,” but “Turn.”

• Turning is a change of direction—away from sin and self toward the Lord Himself (Isaiah 55:6-7; Zechariah 1:3).

• It requires personal response; no one can turn for someone else (Acts 3:19).

• The initiative is God’s. He speaks first, opening the door for all who will listen (Revelation 3:20).

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and be saved

Turning has a goal: salvation.

• Salvation is rescue from the penalty, power, and ultimately the presence of sin (Romans 6:23; Ephesians 2:8-9).

• It is God’s work, not human achievement (Titus 3:4-5).

• The promise is certain; those who turn are not merely offered help—they “be saved” (John 3:16-17).

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all the ends of the earth

The invitation is global and inclusive.

• From the beginning God intended blessing for “all families of the earth” (Genesis 12:3).

• The Psalmist foresaw nations remembering and turning to the LORD (Psalm 22:27-28).

• In Christ this reaches its climax: “a great multitude… from every nation” standing before the throne (Revelation 7:9-10).

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for I am God

The call rests on who He is.

• His absolute existence backs every promise (Exodus 3:14).

• He alone has power to save; idols are powerless, people are helpless (Isaiah 46:9-10).

• Knowing Him is eternal life itself (John 17:3).

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and there is no other

Exclusivity is not arrogance but truth.

• The LORD declares, “Besides Me there is no God” (Isaiah 44:6; Deuteronomy 4:35).

• In the New Testament the same exclusivity centers on Jesus: “There is no other name under heaven… by which we must be saved” (Acts 4:12).

• False gods promise much and deliver nothing; the one true God both promises and fulfills.

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summary

Isaiah 45:22 is God’s universal, exclusive, and gracious call. Everyone, everywhere is commanded to turn to Him alone for salvation, because He alone is God. The verse presents a simple choice: turn and be saved, or cling to empty substitutes and remain lost. The promise stands open today; the only right response is to turn now, trust fully, and rejoice in the God who saves.