In the biblical narrative, protection from deadly plagues is a recurring theme that underscores God's sovereignty, mercy, and the importance of faith and obedience. Throughout Scripture, plagues are often depicted as instruments of divine judgment, yet they also serve as opportunities for God to demonstrate His power and protection over His people.

Old Testament Instances

1. The Plagues of Egypt: One of the most prominent examples of divine protection from plagues is found in the account of the Exodus. God sent ten plagues upon Egypt to compel Pharaoh to release the Israelites from bondage. During these plagues, God made a distinction between the Egyptians and His people. In Exodus 8:22-23 , God declares, "But on that day I will set apart the land of Goshen, where My people are living, so that no swarms of flies will be there, so that you will know that I, the LORD, am in this land. I will make a distinction between My people and your people." This divine protection culminated in the Passover, where the Israelites were instructed to mark their doorposts with the blood of a lamb, sparing them from the plague of the firstborn (Exodus 12:13).

2. The Plague in the Wilderness: In Numbers 16, following the rebellion of Korah, Dathan, and Abiram, a plague broke out among the Israelites. Moses instructed Aaron to take a censer and make atonement for the people, standing between the living and the dead, and the plague was halted (Numbers 16:46-48). This incident highlights the role of intercession and atonement in securing divine protection.

3. David's Census and the Plague: In 2 Samuel 24, King David's decision to conduct a census led to a plague as a consequence of his actions. However, when David repented and built an altar to the LORD, offering sacrifices, God was moved by the prayers for the land, and the plague was stopped (2 Samuel 24:25).

New Testament Perspective

1. Faith and Healing: In the New Testament, while the focus shifts from national deliverance to personal faith, the theme of protection and healing remains. Jesus' ministry is marked by numerous healings, demonstrating His authority over sickness and disease. In Matthew 8:16-17 , it is written, "When evening came, many who were demon-possessed were brought to Him, and He drove out the spirits with a word and healed all the sick. This was to fulfill what was spoken through the prophet Isaiah: 'He took on our infirmities and carried our diseases.'"

2. The Armor of God: Ephesians 6:10-18 provides a metaphorical framework for protection against spiritual and physical adversities, including plagues. Believers are encouraged to "put on the full armor of God" to stand firm against the schemes of the devil, which can include various forms of trials and tribulations.

Principles of Protection

1. Obedience and Faith: Throughout Scripture, obedience to God's commands and faith in His promises are central to experiencing His protection. In Deuteronomy 28, blessings, including protection from diseases, are promised to those who diligently obey the LORD.

2. Prayer and Intercession: The power of prayer and intercession is evident in the biblical accounts of plagues. James 5:16 emphasizes, "The prayer of a righteous man has great power to prevail."

3. Trust in God's Sovereignty: Believers are called to trust in God's sovereignty and His ultimate plan for their lives. Psalm 91 is a profound declaration of God's protection, stating, "He will cover you with His feathers; under His wings you will find refuge; His faithfulness is a shield and rampart" (Psalm 91:4).

In summary, the Bible presents a multifaceted view of protection from deadly plagues, emphasizing God's power, the importance of faith and obedience, and the role of prayer and intercession. These principles offer believers assurance of God's presence and protection amidst life's challenges.