3465. Musia
Lexical Summary
Musia: Mysia

Original Word: Μυσία
Part of Speech: Noun, Feminine
Transliteration: Musia
Pronunciation: moo-SEE-ah
Phonetic Spelling: (moo-see'-ah)
KJV: Mysia
NASB: Mysia
Word Origin: [of uncertain origin]

1. Mysia, a region of Asia Minor

Strong's Exhaustive Concordance
Mysia.

Of uncertain origin; Mysia, a region of Asia Minor -- Mysia.

NAS Exhaustive Concordance
Word Origin
of uncertain origin
Definition
Mysia, a province of Asia Minor
NASB Translation
Mysia (2).

Thayer's Greek Lexicon
STRONGS NT 3465: Μυσία

Μυσία, Μυσιας, , Mysia, a province of Asia Minor on the shore of the Aegean Sea, between Lydia and the Propontis; it had among its cities Pergamum, Troas, and Assos: Acts 16:7f.

Topical Lexicon
Geographical Setting

Mysia lay in the northwest corner of Asia Minor, bordered by the Propontis (Sea of Marmara) to the north, the Aegean Sea to the west, the river Caïcus to the south, and the region of Bithynia to the east. Its landscape ranged from fertile coastal plains to the slopes of Mount Olympus (modern Uludağ). Key cities included Pergamum (later one of the “seven churches” of Revelation), Adramyttium, Assos, and the seaport of Troas. Major Roman roads traversed the region, linking the interior of Asia Minor with the Hellespont and Europe, making Mysia a strategic corridor for commerce and travel.

Historical Background

Originally inhabited by Thracian migrants, Mysia was absorbed into successive empires—Persian, Hellenistic, and finally Roman. Under Rome it became part of the province of Asia. Its mixed population of Greeks, indigenous Mysians, and Roman colonists fostered a cosmopolitan culture receptive to new ideas, including the gospel. Pagan worship featured the Phrygian mother-goddess Cybele, Dionysian rites, and the imperial cult, all providing a vivid backdrop for apostolic ministry.

Biblical Occurrences

The term appears twice, both in Luke’s record of Paul’s second missionary journey:
• “When they came to the border of Mysia, they tried to enter Bithynia, but the Spirit of Jesus would not permit them” (Acts 16:7).
• “So they passed by Mysia and went down to Troas” (Acts 16:8).

The verses describe Paul, Silas, and Timothy traveling westward across Asia Minor after being “strengthened through the faith” of the churches planted earlier (Acts 16:5). Their intention to turn north toward Bithynia was overruled by the Spirit of Jesus, leading them through Mysia to Troas, where Paul received the Macedonian vision that redirected the mission into Europe (Acts 16:9-10).

Missionary Significance

1. Strategic Redirection: Mysia marks the turning point where the gospel, moving steadily west, crossed from Asia to Europe. The Spirit’s restraint in Mysia and invitation in Troas highlight divine sovereignty in missionary strategy.
2. Timing of Harvest: Though Paul merely “passed by” Mysia, seeds were planted. By the time John wrote Revelation, Pergamum had a thriving church (Revelation 2:12-17), showing that God later opened what He first closed.
3. Troas as Launch Point: Situated on Mysia’s coast, Troas became the springboard for evangelization of Macedonia and Greece, illustrating how a seemingly peripheral region facilitated a continental breakthrough.

Theological Themes

• Guidance of the Holy Spirit: The narrative underscores that successful ministry depends not simply on zeal or opportunity but on Spirit-directed timing (Proverbs 16:9; Romans 8:14).
• Obedience over Preference: Paul’s submission to divine restraint models trust in God’s broader plan, even when immediate prospects appear promising.
• Expansion of the Kingdom: Mysia stands as the last Asian threshold before the gospel entered Europe, fulfilling the mandate “to the ends of the earth” (Acts 1:8).

Lessons for Today

• Closed doors can be providential detours leading to greater fruitfulness.
• Regions that seem incidental in one season may become central in another; no place is insignificant in God’s economy.
• Effective missions marry diligent planning with humble responsiveness to the Spirit’s leading.

Related Scriptures

Acts 18:23 – Paul’s later circuit “through the region of Galatia and Phrygia” shows a pattern of Spirit-guided revisits.

Revelation 2:12-17 – Evidence of a mature church in Pergamum, confirming long-term gospel impact in Mysia.

2 Corinthians 2:12-13 – Paul’s sensitivity to open doors (“a door was opened for me in the Lord”) echoes the Mysian experience.

Summary

Mysia, though only a brief stop in Acts, became a pivotal crossroads where divine guidance steered the apostolic mission from Asia to Europe. Its example reminds modern believers that God’s redirection, even through unknown or overlooked regions, furthers His unbroken purpose to spread the gospel to all nations.

Forms and Transliterations
Μυσιαν Μυσίαν μύστακα Musian Mysian Mysían
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Englishman's Concordance
Acts 16:7 N-AFS
GRK: κατὰ τὴν Μυσίαν ἐπείραζον εἰς
NAS: and after they came to Mysia, they were trying
KJV: to Mysia, they assayed
INT: down to Mysia they attempted into

Acts 16:8 N-AFS
GRK: δὲ τὴν Μυσίαν κατέβησαν εἰς
NAS: and passing by Mysia, they came down
KJV: And they passing by Mysia came down to
INT: moreover Mysia they came down to

Strong's Greek 3465
2 Occurrences


Μυσίαν — 2 Occ.

3464
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