475. antidiatithémi
Lexical Summary
antidiatithémi: To oppose, to set oneself against, to arrange in opposition.

Original Word: ἀντιδιατίθημι
Part of Speech: Verb
Transliteration: antidiatithémi
Pronunciation: an-tee-dee-at-EE-thay-mee
Phonetic Spelling: (an-tee-dee-at-eeth'-em-ahee)
KJV: that oppose themselves
NASB: opposition
Word Origin: [from G473 (ἀντί - instead) and G1303 (διατίθεμαι - made)]

1. to set oneself opposite, i.e. be disputatious

Strong's Exhaustive Concordance
that oppose themselves.

From anti and diatithemai; to set oneself opposite, i.e. Be disputatious -- that oppose themselves.

see GREEK anti

see GREEK diatithemai

NAS Exhaustive Concordance
Word Origin
from anti and diatithémi
Definition
to oppose, set oneself in opposition
NASB Translation
opposition (1).

Thayer's Greek Lexicon
STRONGS NT 475: ἀντιδιατίθημι

ἀντιδιατίθημι: (present middle ἀντιδιατίθεμαι); in middle to place oneself in opposition, to oppose: of heretics, 2 Timothy 2:25, cf. DeWette (or Holtzm.) at the passage; (several times in ecclesiastical writings; in the active to dispose in turn, to take in hand in turn: τινα, Diodorus except, p. 602 (vol. v., p. 105, 24, Dindorf edition; absolutely to retaliate, Philo de spec. legg. § 15; de concupisc. § 4)).

Topical Lexicon
Antidiatithemai – Those Who Oppose

Definition and Scope

The verb pictures an active, deliberate setting of oneself against another position. In Scripture it characterizes people who stand in conscious resistance to a gospel messenger or to revealed truth itself.

Biblical Setting in 2 Timothy 2:25

Paul instructs Timothy to deal “with gentleness, instructing those who oppose you. Perhaps God will grant them repentance to know the truth” (2 Timothy 2:25). The clause places three ideas together:

1. Opposition is real and personal.
2. The servant’s posture must remain gentle and instructive, not combative.
3. Divine sovereignty and human responsibility converge, as only God grants repentance while the minister teaches with patience.

Opposition within the Pastoral Epistles

Paul repeatedly warns about quarrels (2 Timothy 2:23), divisive speech (Titus 3:10-11), and false teachers (1 Timothy 6:3-5). Antidiatithemai unites these warnings by showing that error is not merely intellectual but moral; the will sets itself against God’s message.

Historical Context

2 Timothy was penned as Paul faced imminent martyrdom under Nero. Doctrinal erosion had begun infiltrating the Ephesian church. Timothy, younger and frequently timid, needed guidance for confronting men energized by pride and speculative myths (2 Timothy 2:16-18). Antidiatithemai highlights the social pressure Timothy faced: entrenched opposition rather than polite disagreement.

Theological Themes

• Human rebellion versus divine revelation

Antidiatithemai sits within the larger biblical theme of resistance to God (Romans 1:18-25). The heart that refuses light compounds its own darkness until God grants repentance.

• The servant’s character

Spiritual fruit—gentleness, patience, humility—are essential when facing opponents (Galatians 5:22-23; 2 Timothy 2:24). The aim is restoration, not triumph.

• Sovereign grace

Paul’s “perhaps God will grant” underscores that only the Spirit overcomes opposition (John 16:8). This protects ministers from both discouragement and pride.

Old Testament Parallels

Pharaoh “hardened his heart” (Exodus 8:15) and Israel “stiffened their neck” (Nehemiah 9:29). These narratives reveal the same stance of resistance, illustrating the continuity of human obstinacy across covenants.

Christ’s Model toward Opponents

Jesus confronted resistance throughout His ministry yet fulfilled Isaiah’s prophecy: “He will not quarrel or cry out” (Matthew 12:19). Even when rebuking Pharisees, the Lord desired their repentance (Matthew 23:37).

Apostolic Practice

Acts 18:6 – Paul “shook out his clothes” when Jews opposed him, symbolizing accountability.
Acts 19:8-10 – He reasoned daily in the lecture hall after some “hardened themselves and refused to believe.”

These examples show discernment: continuing to teach the willing while not yielding truth to persistent resistance.

Pastoral Counsel for Today’s Church

1. Recognize that opposition often masks spiritual blindness; arguments are symptoms, not root causes.
2. Maintain a posture of meekness; the way truth is delivered affects its reception.
3. Commit adversaries to God in prayer, trusting Him to open hearts.

Related Biblical Concepts

• Antilegō – verbal contradiction (Romans 10:21).
• Anthistēmi – to withstand (James 4:7).
• Apeitheō – disobedience through unbelief (John 3:36).

Together they portray a spectrum of resistance ranging from intellectual dispute to open rebellion.

Doctrinal Significance

Antidiatithemai reminds believers that proclamation and opposition are twin realities until Christ returns. The gospel inevitably clashes with self-rule, but God’s servants must neither compromise truth nor abandon love, displaying the same longsuffering that won their own hearts.

Forms and Transliterations
αντεδίδους αντεδίκησεν αντιδιατιθεμενους αντιδιατιθεμένους ἀντιδιατιθεμένους αντιδικών antidiatithemenous antidiatitheménous
Links
Interlinear GreekInterlinear HebrewStrong's NumbersEnglishman's Greek ConcordanceEnglishman's Hebrew ConcordanceParallel Texts
Englishman's Concordance
2 Timothy 2:25 V-PPM-AMP
GRK: παιδεύοντα τοὺς ἀντιδιατιθεμένους μή ποτε
NAS: those who are in opposition, if perhaps
KJV: instructing those that oppose themselves; if
INT: disciplining those that oppose lest ever

Strong's Greek 475
1 Occurrence


ἀντιδιατιθεμένους — 1 Occ.

474
Top of Page
Top of Page