2361. thrombos
Lexical Summary
thrombos: Drop, Clot

Original Word: θρόμβος
Part of Speech: Noun, Masculine
Transliteration: thrombos
Pronunciation: throm'-bos
Phonetic Spelling: (throm'-bos)
KJV: great drop
NASB: drops
Word Origin: [perhaps from G5142 (τρέφω - feeds) (in the sense of thickening)]

1. a clot

Strong's Exhaustive Concordance
great drop.

Perhaps from trepho (in the sense of thickening); a clot -- great drop.

see GREEK trepho

NAS Exhaustive Concordance
Word Origin
from trephó
Definition
a lump
NASB Translation
drops (1).

Thayer's Greek Lexicon
STRONGS NT 2361: θρόμβος

θρόμβος, θρομβου, (allied with τρέφω in the sense to thicken; Vanicek, p. 307), a large thick drop, especially of clotted blood (Aeschylus Eum. 184); with αἵματος added (Aeschylus choeph. 533, 546; Plato, Critias, p. 120a.), Luke 22:44 (L brackets WH reject the passage (see WH's Appendix at the passage)).

Topical Lexicon
Scriptural Context

Luke 22:44 records the only New Testament use of θρόμβοι (Strong’s Greek 2361): “And being in anguish, He prayed more earnestly, and His sweat became like drops of blood falling to the ground” (Berean Standard Bible). Positioned between the resolve of verse 42 (“not My will, but Yours be done”) and the arrest in verse 47, the word heightens the intensity of Jesus’ vigil in Gethsemane and underscores the costliness of His obedience.

Setting within the Passion Narrative

Luke alone reports both the angelic strengthening (Luke 22:43) and the bloody sweat (Luke 22:44), portraying the scene with physician-like detail (cf. Colossians 4:14). The use of θρόμβοι turns the garden into the threshold of Calvary, revealing that the passion did not begin on Golgotha but in the place of prayer. As Adam fell in a garden (Genesis 3:6), the second Adam conquers in a garden, yet only through an agony that presses blood from His brow.

Medical and Historical Considerations

Ancient writers such as Aristotle and Galen used cognate terms for thickened or congealed blood. Modern medicine recognizes hematidrosis, a rare condition in which extreme stress ruptures capillaries, mingling blood with perspiration. Luke’s notation therefore reflects both clinical possibility and eyewitness precision, while also conveying a theological reality: Christ’s suffering engaged the full extremity of human frailty.

Theological Significance

1. Substitutionary Suffering: The bloody sweat anticipates the shedding of blood required for atonement (Hebrews 9:22). Before a single lash or nail, the Redeemer voluntarily bleeds, portraying His life as the ransom price (Mark 10:45).
2. Perfect Obedience: The phrase “He prayed more earnestly” connects the intensity of prayer with the severity of suffering, demonstrating that obedience is not passive resignation but active devotion (Hebrews 5:7–8).
3. Fulfillment of Prophecy: Isaiah 53:5 predicted a wounding that brings healing. The first literal drops of Messiah’s blood fulfill the prophetic portrait of the Suffering Servant.
4. Spiritual Warfare: The garden scene exposes the cosmic conflict behind the passion (Luke 22:53). The drops of blood witness that victory over the powers of darkness is won through sacrificial submission, not coercive force.

Christological Implications

θρόμβοι validates both the true humanity and the sinless perfection of Christ. Only a genuine human body could experience such somatic trauma; only a perfect will could endure it without rebellion. By recording this detail, Luke offers an antidote to docetic errors that minimize Christ’s fleshly reality and to any theology that detaches redemption from bodily suffering.

Connections with Old Testament Foreshadowing

Genesis 3:19 links sweat with the curse; in Gethsemane the Last Adam bears cursed sweat mingled with redeeming blood, signaling reversal.
Leviticus 16 portrays the high priest entering with blood; in Luke 22 the ultimate High Priest begins His approach to the heavenly sanctuary with blood already upon Him.
Psalm 22:14–15 depicts bodily disintegration; the bloody sweat marks the commencement of that prophetic ordeal.

Pastoral and Devotional Applications

• Comfort in Suffering: Believers facing extreme distress can look to a Savior who has endured agony to the point of blood (Hebrews 12:3–4).
• Call to Fervent Prayer: The Lord’s earnest prayer under crushing pressure models perseverance for the church (Luke 18:1; Ephesians 6:18).
• Assurance of Redemption: Every drop that fell in Gethsemane testifies that salvation is grounded not in human resolve but in divine sacrifice.

Relation to Christian Suffering

Peter admonishes, “For to this you were called, because Christ suffered for you, leaving you an example” (1 Peter 2:21). θρόμβοι reveals that the pathway of the Messiah—and therefore of His disciples—may include anguish, yet such anguish is never purposeless. Suffering joined to obedience is woven into God’s redemptive design (Romans 8:17–18).

Doctrinal Reflections

The presence of θρόμβοι strengthens doctrines of:
• Incarnation: affirming full participation in human condition.
• Atonement: highlighting both the necessity and sufficiency of Christ’s blood.
• Perseverance: demonstrating that grace empowers fidelity under maximal pressure.
• Revelation: endorsing the harmony of medical realism and divine inspiration within Scripture.

Thus the solitary occurrence of θρόμβοι serves as a profound witness to the incarnate Son’s voluntary, bodily, and substitutionary suffering—blood that began to flow in Gethsemane and reached its consummation on the cross, securing eternal redemption for all who believe.

Forms and Transliterations
θρομβοι θρόμβοι thromboi thrómboi
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Interlinear GreekInterlinear HebrewStrong's NumbersEnglishman's Greek ConcordanceEnglishman's Hebrew ConcordanceParallel Texts
Englishman's Concordance
Luke 22:44 N-NMP
GRK: αὐτοῦ ὡσεὶ θρόμβοι αἵματος καταβαίνοντες
NAS: like drops of blood,
KJV: as it were great drops of blood
INT: of him as great drops of blood falling down

Strong's Greek 2361
1 Occurrence


θρόμβοι — 1 Occ.

2360
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