Isaiah 51:21
New International Version
Therefore hear this, you afflicted one, made drunk, but not with wine.

New Living Translation
But now listen to this, you afflicted ones who sit in a drunken stupor, though not from drinking wine.

English Standard Version
Therefore hear this, you who are afflicted, who are drunk, but not with wine:

Berean Standard Bible
Therefore now hear this, you afflicted one, drunken, but not with wine.

King James Bible
Therefore hear now this, thou afflicted, and drunken, but not with wine:

New King James Version
Therefore please hear this, you afflicted, And drunk but not with wine.

New American Standard Bible
Therefore, listen to this, you afflicted, Who are drunk, but not with wine:

NASB 1995
Therefore, please hear this, you afflicted, Who are drunk, but not with wine:

NASB 1977
Therefore, please hear this, you afflicted, Who are drunk, but not with wine:

Legacy Standard Bible
Therefore, now, listen to this, you afflicted, Who are drunk, but not with wine:

Amplified Bible
Therefore, now hear this, you who are afflicted, Who are drunk, but not with wine [but overwhelmed by the wrath of God].

Christian Standard Bible
So listen to this, suffering and drunken one—but not with wine.

Holman Christian Standard Bible
So listen to this, afflicted and drunken one—but not with wine.

American Standard Version
Therefore hear now this, thou afflicted, and drunken, but not with wine:

Contemporary English Version
You are in trouble and drunk, but not from wine. So pay close attention

English Revised Version
Therefore hear now this, thou afflicted, and drunken, but not with wine:

GOD'S WORD® Translation
Listen to this, you humble people who are drunk but not from wine.

Good News Translation
You suffering people of Jerusalem, you that stagger as though you were drunk,

International Standard Version
Now listen to this, you afflicted one, made drunk, but not with wine:

NET Bible
So listen to this, oppressed one, who is drunk, but not from wine!

New Heart English Bible
Therefore hear now this, you afflicted, and drunk, but not with wine:

Webster's Bible Translation
Therefore hear now this, thou afflicted, and drunken, but not with wine:
Majority Text Translations
Majority Standard Bible
Therefore now hear this, you afflicted one, drunken, but not with wine.

World English Bible
Therefore now hear this, you afflicted, and drunken, but not with wine:
Literal Translations
Literal Standard Version
Therefore, please hear this, "" O afflicted and drunken one, and not with wine,

Young's Literal Translation
Therefore, hear, I pray thee, this, O afflicted and drunken one, and not with wine,

Smith's Literal Translation
For this, bear now this, thou afflicted and drunken, and not from wine:
Catholic Translations
Douay-Rheims Bible
Therefore hear this, thou poor little one, and thou that art drunk but no with wine.

Catholic Public Domain Version
Therefore, listen to this, O poor little ones, and you who have been inebriated, but not by wine.

New American Bible
But now, hear this, afflicted one, drunk, but not with wine,

New Revised Standard Version
Therefore hear this, you who are wounded, who are drunk, but not with wine:
Translations from Aramaic
Lamsa Bible
Therefore hear now this, O you afflicted and drunken, but not with wine;

Peshitta Holy Bible Translated
Because of this, hear these things, afflicted ones who are drunk, not from wine
OT Translations
JPS Tanakh 1917
Therefore hear now this, thou afflicted, And drunken, but not with wine;

Brenton Septuagint Translation
Therefore hear, thou afflicted one, and drunken, but not with wine;

Additional Translations ...
Audio Bible



Context
The Cup of Wrath
20Your sons have fainted; they lie at the head of every street, like an antelope in a net. They are full of the wrath of the LORD, the rebuke of your God. 21Therefore now hear this, you afflicted one, drunken, but not with wine. 22Thus says your Lord, the LORD, even your God, who defends His people: “See, I have removed from your hand the cup of staggering. From that goblet, the cup of My fury, you will never drink again.…

Cross References
Isaiah 54:11
“O afflicted city, lashed by storms, without solace, surely I will set your stones in antimony and lay your foundations with sapphires.

Isaiah 40:1-2
“Comfort, comfort My people,” says your God. / “Speak tenderly to Jerusalem, and proclaim to her that her forced labor has been completed; her iniquity has been pardoned. For she has received from the hand of the LORD double for all her sins.”

Jeremiah 30:10-11
As for you, O Jacob My servant, do not be afraid, declares the LORD, and do not be dismayed, O Israel. For I will surely save you out of a distant place, your descendants from the land of their captivity! Jacob will return to quiet and ease, with no one to make him afraid. / For I am with you to save you, declares the LORD. Though I will completely destroy all the nations to which I have scattered you, I will not completely destroy you. Yet I will discipline you justly, and will by no means leave you unpunished.”

Lamentations 1:12
Is this nothing to you, all you who pass by? Look around and see! Is there any sorrow like mine, which was inflicted on me, which the LORD made me suffer on the day of His fierce anger?

Ezekiel 36:3-7
therefore prophesy and declare that this is what the Lord GOD says: Because they have made you desolate and have trampled you on every side, so that you became a possession of the rest of the nations and were taken up in slander by the lips of their talkers, / therefore, O mountains of Israel, hear the word of the Lord GOD. This is what the Lord GOD says to the mountains and hills, to the ravines and valleys, to the desolate ruins and abandoned cities, which have become a spoil and a mockery to the rest of the nations around you. / Therefore this is what the Lord GOD says: Surely in My burning zeal I have spoken against the rest of the nations, and against all Edom, who took My land as their own possession with wholehearted joy and utter contempt, so that its pastureland became plunder. ...

Zechariah 1:15-17
but I am fiercely angry with the nations that are at ease. For I was a little angry, but they have added to the calamity.’ / Therefore this is what the LORD says: ‘I will return to Jerusalem with mercy, and there My house will be rebuilt, declares the LORD of Hosts, and a measuring line will be stretched out over Jerusalem.’ / Proclaim further that this is what the LORD of Hosts says: ‘My cities will again overflow with prosperity; the LORD will again comfort Zion and choose Jerusalem.’”

Psalm 102:13-17
You will rise up and have compassion on Zion, for it is time to show her favor—the appointed time has come. / For Your servants delight in her stones and take pity on her dust. / So the nations will fear the name of the LORD, and all the kings of the earth will fear Your glory. ...

Psalm 9:9-10
The LORD is a refuge for the oppressed, a stronghold in times of trouble. / Those who know Your name trust in You, for You, O LORD, have not forsaken those who seek You.

Psalm 34:17-19
The righteous cry out, and the LORD hears; He delivers them from all their troubles. / The LORD is near to the brokenhearted; He saves the contrite in spirit. / Many are the afflictions of the righteous, but the LORD delivers him from them all.

Psalm 107:39-41
When they are decreased and humbled by oppression, evil, and sorrow, / He pours out contempt on the nobles and makes them wander in a trackless wasteland. / But He lifts the needy from affliction and increases their families like flocks.

Matthew 5:4
Blessed are those who mourn, for they will be comforted.

Luke 4:18-19
“The Spirit of the Lord is on Me, because He has anointed Me to preach good news to the poor. He has sent Me to proclaim liberty to the captives and recovery of sight to the blind, to release the oppressed, / to proclaim the year of the Lord’s favor.”

John 14:27
Peace I leave with you; My peace I give to you. I do not give to you as the world gives. Do not let your hearts be troubled; do not be afraid.

Romans 8:35-39
Who shall separate us from the love of Christ? Shall trouble or distress or persecution or famine or nakedness or danger or sword? / As it is written: “For Your sake we face death all day long; we are considered as sheep to be slaughtered.” / No, in all these things we are more than conquerors through Him who loved us. ...

2 Corinthians 1:3-4
Blessed be the God and Father of our Lord Jesus Christ, the Father of compassion and the God of all comfort, / who comforts us in all our troubles, so that we can comfort those in any trouble with the comfort we ourselves have received from God.


Treasury of Scripture

Therefore hear now this, you afflicted, and drunken, but not with wine:

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Isaiah 51
1. An exhortation after the pattern of Abraham, to trust in Christ
3. By reason of his comfortable promises,
4. Of his righteous salvation
7. And man's mortality
9. Christ by his sanctified arm defends his from the fear of man
17. He bewails the afflictions of Jerusalem
21. And promises deliverance














Therefore now hear this
This phrase serves as a call to attention, indicating a shift or important message from God. It is a common prophetic introduction, emphasizing the authority and urgency of the message. In the context of Isaiah, it often precedes a message of hope or judgment. The use of "therefore" connects this message to the preceding verses, which speak of God's comfort and redemption for His people.

you afflicted one
The term "afflicted" refers to the suffering and oppressed state of the Israelites during their exile. Historically, this period was marked by the Babylonian captivity, where the Israelites faced hardship and loss of identity. Theologically, it reflects the consequences of sin and disobedience, yet also sets the stage for divine intervention and restoration. This affliction is both physical and spiritual, symbolizing the broader human condition in need of God's salvation.

drunken, but not with wine
This metaphorical language describes a state of confusion and disorientation, not caused by literal intoxication but by overwhelming circumstances and divine judgment. In the Bible, drunkenness often symbolizes spiritual blindness or moral decay (e.g., Isaiah 29:9-10). Here, it underscores the depth of Israel's distress and their inability to find their own way out. It also points to the need for divine clarity and deliverance, which God promises to provide. This imagery can be seen as a type of Christ, who offers true spiritual clarity and freedom from the bondage of sin.

Persons / Places / Events
1. The Afflicted One
This refers to the people of Israel who are experiencing suffering and hardship. They are described as being in a state of distress and turmoil.

2. Jerusalem
The city represents the heart of the Jewish nation, often personified in the prophetic books as a woman who experiences both the judgment and the mercy of God.

3. The Prophet Isaiah
The author of the book, Isaiah is delivering God's message to the people of Israel, calling them to listen and understand their current state and the hope that lies ahead.

4. The Babylonian Captivity
This historical context is significant as the Israelites were exiled and faced great suffering, which is metaphorically described as being "drunken, but not with wine."

5. God's Promise of Redemption
The overarching event in this passage is the promise of deliverance and restoration for God's people, despite their current afflictions.
Teaching Points
Understanding Spiritual Intoxication
The phrase "drunken, but not with wine" symbolizes spiritual confusion and disorientation. Believers should be aware of the influences that lead them away from God's truth and seek clarity through His Word.

God's Compassion for the Afflicted
Despite the afflictions faced, God hears and responds to the cries of His people. This teaches us about God's compassion and the importance of turning to Him in times of distress.

The Promise of Redemption
God's message through Isaiah is one of hope and restoration. Believers can find assurance in God's promises, knowing that He will ultimately deliver and restore His people.

Listening to God's Voice
The call to "hear this" emphasizes the importance of being attentive to God's Word. In our spiritual journey, we must prioritize listening to God's guidance and instruction.

The Role of Prophetic Messages
Isaiah's role as a prophet highlights the importance of prophetic messages in guiding and correcting God's people. We should value and heed the teachings of Scripture as they reveal God's will.
Bible Study Questions and Answers
1. What is the meaning of Isaiah 51:21?

2. How does Isaiah 51:21 encourage us to trust in God's deliverance today?

3. What does "afflicted and drunken, but not with wine" symbolize in our lives?

4. How can Isaiah 51:21 deepen our understanding of God's compassion for His people?

5. How does Isaiah 51:21 connect with Jesus' promise of rest in Matthew 11:28?

6. How can we apply God's reassurance in Isaiah 51:21 to our current struggles?

7. What is the historical context of Isaiah 51:21 in the Bible?

8. How does Isaiah 51:21 reflect God's relationship with Israel?

9. What theological themes are present in Isaiah 51:21?

10. What are the top 10 Lessons from Isaiah 51?

11. What is the Christian Perspective on drinking wine?

12. What are Christ's active and passive obedience?

13. What is the Bible's perspective on healthcare?

14. In Matthew 26:36-46, why does Jesus seem conflicted about His fate if He was fully aware of His divine mission and outcome?
What Does Isaiah 51:21 Mean
Therefore now hear this

- “Therefore” ties verse 21 to the warning in verses 17-20: Jerusalem has drained “the cup of the LORD’s wrath” (v.17). The word signals a turning point—because judgment has accomplished its purpose, God now speaks comfort.

- “Now” underscores urgency; the moment for relief has arrived (cf. Isaiah 55:6; 2 Corinthians 6:2).

- “Hear” is the same summons the LORD uses throughout Scripture when He wants His people to receive life-giving truth (Deuteronomy 32:1; Isaiah 46:3; Revelation 2:7). Listening is the first step toward restoration.

- “This” points ahead to verses 22-23, where God promises to take the cup from their hand and place it in the hand of their tormentors—assurance that deliverance is imminent.


you afflicted one

- The phrase addresses Zion—God’s covenant people—crushed by exile, oppression, and shame (Isaiah 49:13; Lamentations 1:12).

- Their affliction is real yet purposeful: the LORD disciplines those He loves (Hebrews 12:6; Psalm 119:67).

- Even in hardship, He never forgets His own (Psalm 34:19; Exodus 3:7). He sees, names, and comforts the afflicted, reminding them they are still His treasured possession.

- This tender designation foreshadows later promises: “O afflicted city, lashed by storms… I will rebuild you with stones of turquoise” (Isaiah 54:11-12).


drunken, but not with wine

- The imagery recalls 51:17—Jerusalem staggered because she “drank to the dregs” the cup of divine wrath. Their stupor is spiritual and emotional, not alcoholic (Isaiah 29:9-10).

- Scripture often pictures judgment as forced intoxication: Jeremiah 25:15-16; Psalm 60:3; Revelation 16:19. Here God explains why His people reel: judgment, not self-indulgence.

- Yet the sentence is temporary. Verse 22 announces, “Behold, I have taken from your hand the cup of staggering.” Ultimately, Christ drains that cup for us (Matthew 26:39), securing freedom from condemnation (Romans 8:1).

- Practical takeaway: when life leaves us reeling, the cause may be divine correction meant to drive us back to the One who offers true soberness and peace (1 Peter 5:10).


summary

Isaiah 51:21 is God’s compassionate call to a battered, bewildered people. Having allowed severe discipline, He now commands them to listen because relief is on the way. He identifies them as “afflicted,” proving He knows their pain, and describes their staggering condition as the result of His righteous judgment, not mere excess. The verse prepares hearts for the promise that follows: God Himself will remove the cup of wrath and restore His people. In Christ, that promise finds its fullest expression, assuring believers that the same Lord who disciplines also delivers, comforts, and restores.

(21) Drunken, but not with wine . . .--Same phrase as in Isaiah 29:9.

Verse 21. - Drunken, but not with wine (comp. Isaiah 29:9; and see above, ver. 17, which shows that the appearance of drunkenness had been produced by Jerusalem drinking the cup of God's wrath).

Parallel Commentaries ...


Hebrew
Therefore
לָכֵ֛ן (lā·ḵên)
Adverb
Strong's 3651: So -- thus

now
נָ֥א (nā)
Interjection
Strong's 4994: I pray', 'now', 'then'

hear
שִׁמְעִי־ (šim·‘î-)
Verb - Qal - Imperative - feminine singular
Strong's 8085: To hear intelligently

this,
זֹ֖את (zōṯ)
Pronoun - feminine singular
Strong's 2063: Hereby in it, likewise, the one other, same, she, so much, such deed, that,

you afflicted one,
עֲנִיָּ֑ה (‘ă·nî·yāh)
Adjective - feminine singular
Strong's 6041: Poor, afflicted, humble

drunken,
וּשְׁכֻרַ֖ת (ū·šə·ḵu·raṯ)
Conjunctive waw | Adjective - feminine singular construct
Strong's 7937: To become tipsy, to satiate with a, stimulating drink, influence

but not
וְלֹ֥א (wə·lō)
Conjunctive waw | Adverb - Negative particle
Strong's 3808: Not, no

with wine.
מִיָּֽיִן׃ (mî·yā·yin)
Preposition-m | Noun - masculine singular
Strong's 3196: Wine, intoxication


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OT Prophets: Isaiah 51:21 Therefore hear now this you afflicted (Isa Isi Is)
Isaiah 51:20
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