5424. phrén
Lexical Summary
phrén: Mind, understanding, intellect

Original Word: φρήν
Part of Speech: Noun, Feminine
Transliteration: phrén
Pronunciation: frane
Phonetic Spelling: (frane)
KJV: understanding
NASB: thinking
Word Origin: [probably from an obsolete phrao "to rein in or curb"]

1. the midrif (as a partition of the body)
2. (figuratively and by implication of sympathy) the feelings or sensitive nature
3. (by extension, also in the plural) the mind or cognitive faculties

Strong's Exhaustive Concordance
understanding.

Probably from an obsolete phrao (to rein in or curb; compare phrasso); the midrif (as a partition of the body), i.e. (figuratively and by implication, of sympathy) the feelings (or sensitive nature; by extension (also in the plural) the mind or cognitive faculties) -- understanding.

see GREEK phrasso

HELPS Word-studies

Cognate: 5424 phrḗn (a feminine noun) – properly, "the midriff (diaphragm), the parts around the heart" (J. Thayer); (figuratively) visceral (personal) opinion; what a person "really has in mind," i.e. inner outlook (mind-set, insight) that regulates outward behavior. See 5429 (phronimos).

[5424 (phrḗn) is the root of the English term, "diaphragm," which regulates breathing.]

NAS Exhaustive Concordance
Word Origin
a prim. word
Definition
midriff, heart, mind, thought
NASB Translation
thinking (2).

Thayer's Greek Lexicon
STRONGS NT 5424: φρήν

φρήν, φρενος, , plural φρένες, from Homer down, the Sept. several times in Proverbs for לֵב:

1. the midriff or diaphragm, the parts about the heart.

2. the mind; the faculty of perceiving and judging: also in the plural; as, 1 Corinthians 14:20.

Topical Lexicon
Concept of Mind in Biblical Anthropology

Strong’s 5424 draws attention to the inner faculty where thought, perception, and moral reflection converge. Scripture presents humanity as both spiritual and rational; therefore, the “mind” is never portrayed as a morally neutral data-processor. It is either yielded to God (Romans 8:6) or darkened by sin (Ephesians 4:17–18). The term behind 5424 highlights the seat of deliberate judgment, distinguishing it from mere instinct or emotion and setting a foundation for New Covenant teaching on renewal of the mind (Romans 12:2).

Occurrences in the New Testament

Paul employs the word twice in a single sentence:

“Brothers, stop thinking like children. In regard to evil be infants, but in your thinking be mature” (1 Corinthians 14:20).

By repeating the noun, he contrasts two modes of existence: naïve innocence toward evil versus grown-up discernment in congregational life. The immediate context is the use of spiritual gifts; the broader point is that Christian worship must arise from a mind trained by truth, not from childish fascination with the spectacular.

Relation to Spiritual Maturity

Paul’s call to be “mature in mind” assumes a developmental trajectory: believers move from infancy to adulthood through exposure to sound doctrine (Hebrews 5:12–14). Maturity is measured not by years in the faith but by the ability to evaluate teachings, govern impulses, and edify the body. The repetition of 5424 underscores that such maturity is cognitive, not merely emotional; it requires intentional cultivation.

Historical and Theological Development

Early church writers drew on 1 Corinthians 14:20 to balance mystical experience with doctrinal sobriety. Clement of Alexandria cited the verse to argue that true gnosis is inseparable from moral purity. Augustine appealed to it against the excesses of certain charismatic movements, insisting that the Spirit never bypasses the sanctified mind. The Reformers later used the passage to affirm that Scripture, illumined by the Spirit, equips believers with “sound reason sanctified,” guarding against both rationalism and anti-intellectualism.

Pastoral and Discipleship Implications

1. Teaching ministries must aim at transforming the mind, not merely imparting information.
2. Leaders should encourage discernment in worship practices, ensuring intelligibility and edification (1 Corinthians 14:9).
3. Children’s innocence toward evil is commendable, yet remaining childlike in understanding is not; programs for all ages should progressively deepen theological comprehension.

Practical Application in the Local Church

• Small-group studies can pair doctrinal lessons with case studies that exercise moral reasoning.
• Corporate prayer may include petitions for renewed minds (Ephesians 1:17–18).
• Elders can model decision-making that weighs biblical principles rather than personal preference, illustrating mature “thinking” in action.

Comparative Scriptural Usage

Although 5424 itself appears only in 1 Corinthians 14:20, related forms (e.g., phroneo, phronema) illuminate its sphere:
Romans 8:6 contrasts “the mind of the flesh” with “the mind of the Spirit.”
Philippians 2:5 commands, “Let this mind be in you which was also in Christ Jesus,” linking sanctified thinking to Christlike humility.

These parallels reinforce Paul’s expectation that cognitive renewal fuels practical holiness.

Conclusion

Strong’s 5424 concentrates the biblical vision of a mind redeemed for God’s glory. Paul’s twin use of the term calls every believer to childlike purity toward evil yet full-grown discernment in every other respect—a balance that safeguards both doctrinal fidelity and vibrant spiritual life.

Forms and Transliterations
φρένες φρενών φρεσί φρεσιν φρεσίν φρεσὶν φρίκη φρίκην φρικτά φρικώδη phresin phresín phresìn
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Englishman's Concordance
1 Corinthians 14:20 N-DFP
GRK: γίνεσθε ταῖς φρεσίν ἀλλὰ τῇ
NAS: do not be children in your thinking; yet
KJV: children in understanding: howbeit
INT: be in the minds but in the [regard to]

1 Corinthians 14:20 N-DFP
GRK: ταῖς δὲ φρεσὶν τέλειοι γίνεσθε
NAS: be infants, but in your thinking be mature.
KJV: but in understanding be
INT: in the [regard to] however thinking full grown be

Strong's Greek 5424
2 Occurrences


φρεσίν — 2 Occ.

5423
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