480. antikeimai
Lexical Summary
antikeimai: To oppose, to be set against, to resist

Original Word: ἀντίκειμαι
Part of Speech: Verb
Transliteration: antikeimai
Pronunciation: an-TEE-kay-my
Phonetic Spelling: (an-tik'-i-mahee)
KJV: adversary, be contrary, oppose
NASB: opponents, adversaries, contrary, enemy, opposes, opposition
Word Origin: [from G473 (ἀντί - instead) and G2749 (κεῖμαι - laid)]

1. to lie opposite, i.e. be adverse to
2. (figuratively) repugnant to

Strong's Exhaustive Concordance
be contrary, oppose.

From anti and keimai; to lie opposite, i.e. Be adverse (figuratively, repugnant) to -- adversary, be contrary, oppose.

see GREEK anti

see GREEK keimai

HELPS Word-studies

480 antíkeimai (from 473 /antí, "against" and 2743 /kautēriázō, "to place") – properly, place fully against, constitutionally oppose – like someone being thoroughly unreconcilable ("intractable, implacable").

NAS Exhaustive Concordance
Word Origin
from anti and keimai
Definition
to lie opposite, i.e. oppose, withstand
NASB Translation
adversaries (1), contrary (1), enemy (1), opponents (3), opposes (1), opposition (1).

Thayer's Greek Lexicon
STRONGS NT 480: ἀντίκειμαι

ἀντίκειμαι;

1. to be set over against, lie opposite to, in a local sense ((Hippocrates de aëre, p. 282 Foes. (191 Chart.); Strabo 7, 7, 5); Herodian, 6, 2, 4 (2 Bekker); 3, 15, 17 (8 Bekker); (cf. Aristotle, de caelo 1, 8, p. 277{a}, 23)).

2. to oppose, be adverse to, withstand: τίνι, Luke 13:17; Luke 21:15; Galatians 5:17; 1 Timothy 1:10. simply () ἀντικείμενος, an adversary, (Tittmann 2:9): 1 Corinthians 16:9; Philippians 1:28; 2 Thessalonians 2:4; 1 Timothy 5:14. (Dio Cass. 39, 8. Exodus 23:22; 2 Macc. 10:26, etc.; (see Sophocles' Lexicon, under the word).)

Topical Lexicon
Overview

Strong’s Greek 480 depicts active, entrenched opposition—persons, powers, impulses, or systems “lying opposite” to God’s purposes. The term appears eight times in the New Testament and stretches from the earthly ministry of Jesus to the climactic rebellion of the last days. Together the occurrences paint a coherent biblical portrait of conflict that is at once missional, moral, doctrinal, and eschatological.

Occurrences and Narrative Settings

Luke 13:17 – Religious leaders who condemn Sabbath healing are unmasked as adversaries and publicly shamed.
Luke 21:15 – Jesus promises His followers such Spirit-given wisdom that “none of your adversaries will be able to resist or contradict”.
1 Corinthians 16:9 – Paul meets “many” adversaries even while a wide door for ministry stands open at Ephesus.
Philippians 1:28 – Congregational steadfastness in suffering becomes “a clear sign” to opponents of their destruction and of the saints’ salvation.
Galatians 5:17 – The flesh and the Spirit are pictured as mutually opposing forces within the believer.
1 Timothy 1:10 – Unsound lifestyles and teachings stand contrary to sound doctrine.
1 Timothy 5:14 – Careful household management is urged “to give the enemy no occasion for reproach,” recognizing Satan’s use of human slander.
2 Thessalonians 2:4 – The man of lawlessness “will oppose and exalt himself above every so-called god,” the ultimate embodiment of antichrist opposition.

Theological Themes

1. Conflict Is Inevitable in Gospel Advance

From Jesus’ synagogue confrontation (Luke 13) to Paul’s open door at Ephesus (1 Corinthians 16), Scripture assumes that effective ministry attracts resistance. Opposition, therefore, is not a sign of divine displeasure but a predictable backdrop for fruitful labor.

2. Divine Provision in the Face of Adversaries

Luke 21:15 grounds the believer’s confidence in Christ’s promise: the same Lord who faced adversaries equips His witnesses with irrefutable wisdom. Philippians 1:28 extends that assurance collectively—steadfast unity is itself a God-given testimony against opponents.

3. Internal Versus External Opposition

Galatians 5:17 broadens the word’s scope to the believer’s inner life, reminding disciples that the fiercest struggles may arise within. External persecution and internal fleshly desire share a common root: resistance to the Spirit’s rule.

4. Doctrinal Integrity

In 1 Timothy 1:10 the word highlights lifestyles and teachings that clash with “sound doctrine.” The pastoral letters insist that truth is not merely professed but protected against all that lies in opposition, whether moral perversion or theological error.

5. Eschatological Antagonist

2 Thessalonians 2:4 lifts the concept to its climactic height. The man of lawlessness personifies ultimate rebellion, setting himself “in God’s temple” and demanding worship. The passage links present conflicts with the final apostasy, urging vigilance until Christ’s return.

Historical Background

Greco-Roman civic religion prized social conformity; Christian exclusivity provoked accusation of impiety. Opposition was often legal, economic, or rhetorical. Paul’s experiences in Ephesus (Acts 19) illustrate the milieu behind 1 Corinthians 16:9, where trade guilds, magistrates, and mob sentiment fused into organized resistance.

Practical Ministry Implications

• Expect resistance; measure opportunity by openness, not ease.
• Trust Christ for words and wisdom under pressure (Luke 21:15).
• Guard doctrine; lifestyles opposed to biblical teaching erode gospel credibility (1 Timothy 1:10).
• Engage spiritual disciplines that crucify the flesh so that inner opposition diminishes (Galatians 5:17).
• Encourage congregations that persecution is a “sign…of your salvation” (Philippians 1:28).
• Teach eschatology realistically: current opposition foreshadows a final, focused rebellion yet cannot overturn God’s plan (2 Thessalonians 2).

Key Points for Teaching and Preaching

1. Opposition is not accidental but woven into redemptive history.
2. Victory is promised, not by human ingenuity, but by divine empowerment.
3. The same term embraces personal temptation, societal hostility, and end-time rebellion, showing one coherent conflict.
4. Faithful response includes proclamation, perseverance, purity, and preparedness for Christ’s return.

Strong’s 480 thus joins together the adversaries of Jesus, the trials of the apostles, the battle within every believer, and the climactic foe of the last days—yet in every scene Scripture testifies that the opposition is temporary and overmatched by the sovereign grace and purpose of God.

Forms and Transliterations
αντικείμενά αντικειμενοι αντικείμενοι αντικείμενοί ἀντικείμενοι αντικειμένοις αντικειμενος αντικείμενος ἀντικείμενος αντικειμενω αντικειμένω ἀντικειμένῳ αντικειμενων αντικειμένων ἀντικειμένων αντίκεισαί αντικείσθαι αντικείσομαι αντικειται αντίκειται ἀντίκειται αντικρινόμενός αντικρινούμαι antikeimeno antikeimenō antikeimenoi antikeiménoi antikeiménōi antikeímenoi antikeimenon antikeimenōn antikeiménon antikeiménōn antikeimenos antikeímenos antikeitai antíkeitai
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Englishman's Concordance
Luke 13:17 V-PPM/P-NMP
GRK: πάντες οἱ ἀντικείμενοι αὐτῷ καὶ
NAS: all His opponents were being humiliated;
KJV: all his adversaries were ashamed: and
INT: all who were opposed to him and

Luke 21:15 V-PPM/P-NMP
GRK: ἅπαντες οἱ ἀντικείμενοι ὑμῖν
NAS: none of your opponents will be able
KJV: all your adversaries shall not
INT: all those opposing you

1 Corinthians 16:9 V-PPM/P-NMP
GRK: ἐνεργής καὶ ἀντικείμενοι πολλοί
NAS: to me, and there are many adversaries.
KJV: and [there are] many adversaries.
INT: efficient and opposers [are] many

Galatians 5:17 V-PIM/P-3S
GRK: γὰρ ἀλλήλοις ἀντίκειται ἵνα μὴ
NAS: for these are in opposition to one another,
KJV: these are contrary the one to the other:
INT: indeed to one another are opposed that not

Philippians 1:28 V-PPM/P-GMP
GRK: ὑπὸ τῶν ἀντικειμένων ἥτις ἐστὶν
NAS: alarmed by [your] opponents-- which
KJV: by your adversaries: which
INT: by those who oppose which is

2 Thessalonians 2:4 V-PPM/P-NMS
GRK: ἀντικείμενος καὶ ὑπεραιρόμενος
NAS: who opposes and exalts himself above
KJV: Who opposeth and exalteth
INT: he who opposes and exalts himself

1 Timothy 1:10 V-PIM/P-3S
GRK: ὑγιαινούσῃ διδασκαλίᾳ ἀντίκειται
NAS: else is contrary to sound
KJV: other thing that is contrary to sound
INT: being sound teaching is opposed to

1 Timothy 5:14 V-PPM/P-DMS
GRK: διδόναι τῷ ἀντικειμένῳ λοιδορίας χάριν
NAS: [and] give the enemy no
KJV: occasion to the adversary to
INT: to give to the adversary of insult on account

Strong's Greek 480
8 Occurrences


ἀντικειμένῳ — 1 Occ.
ἀντικειμένων — 1 Occ.
ἀντικείμενοι — 3 Occ.
ἀντικείμενος — 1 Occ.
ἀντίκειται — 2 Occ.

479
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